The power of structural biology techniques and biophysical methods used to characterize the structure and function of biomolecules is unparalleled in the scientific community. Textbooks and journal articles are filled with images of the 3D structures of molecules ranging in size from ATP to DNA to proteins to viruses. Yet, while structure determination methods such as X-ray crystallography and cryo-EM have become common methods for those seeking advanced degrees and training in the life sciences, such as graduate programs and postdoctoral fellowships, it is rare to find undergraduates with significant knowledge or training in any of the structural biology methods including X-ray crystallography, high-resolution cryo-EM, NMR spectroscopy, AFM, small-angle X-ray scattering, micro-electron diffraction or computational biology.

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This 10-week summer undergraduate research program will bridge this education gap by establishing a framework that integrates research projects aimed at studying the structure and function of macromolecules with in-depth workshops designed to provide theoretical and practical training in contemporary structural biology techniques and biophysical methods.  The goal is that each trainee will leave the program with a solid foundation and understanding of the various structural biology methods regardless of the expertise within their host lab.

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Included in the #REUinSCBB:

​Weekly team-building and networking activities

Weekly half-day workshops in SCBB methods (cryo-EM, X-ray crystallography, etc)

Weekly career and professional workshops

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Important Dates: 

Application OPEN | March 11, 2026

Application DEADLINE | April 30, 2026

Decision Notifications START | typically within 1 week of Zoom interview

Program Dates | May 25 - July 31, 2026

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Applicant Eligibility:

Applicants must be citizens or permanent residents of the United States and have a minimum grade point average of 3.0 on a 4.0 scale. Additionally, the applicants must have at least one semester of undergraduate study remaining after completing the summer program and fulfill the NSF citizenship requirements. Students who have received their bachelor's degree and no longer enrolled in an undergraduate study program are generally not eligible.

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Program Support:

Weekly stipend + meals ($900 per week)

FREE Housing provided (single room)

Travel allowance to/from Purdue ($700)

Up to $1000 towards travel support to attend a local/national conference (from faculty host lab)

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​​The Application:

Eligible students are expected to be able to demonstrate an interest in research within the life sciences, particularly in structural and computational biology and biophysics, with preferred prerequisites in biology, biochemistry, chemistry, physics, and mathematics; although not required. Each application will be assessed on an individual basis which will also include previous research experience and letters of recommendation from faculty or instructors.

 

The application consists of (1) a brief questionnaire, (2) a statement of career goals and reasons for participating in the program, and (3) at least two faculty recommendation letters. Applicants must also provide a transcript of their grades and a resume/CV.

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(updated March 11, 2026: our program was just renewed for another 3-years!)

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The Selection Process:

Each application will be reviewed and scored by the REU in SCBB selection committee using a set rubric. Top applicants will then undergo Zoom interviews to assist in identifying students that are most suited to participate in our intense program. Applicants will ideally be notified of a decision within one week after the interview. Admission into the program will be on a rolling basis and continue until all available slots are filled for each year.