04/20|Claire and Evan both passed their prelims and Shubham joins the lab!
Congrats to these two as they advance to candidacy! We also had a new grad student join this semester. Welcome Shubham!
011/19|Karthik, Evan, and Runrun attend the 2019 EverythingBioSAXS workshop at APS!
This workshop provides an introduction to "everything" about small angle X-ray scattering for biomolecules. This 5th annual workshop offers insight into the theory and practice....more.
08/19|We're awarded our second RO1 and Karl joins the lab!
We have received our second R01 from NIH/NIGMS to study the mechanism of OMP biogenesis by the BAM complex! Our goal is to use biochemical techniques to.... more.
Kammerman, M, Bera, A, Wu, R, Harrison, S, Maxwell, N, Lundquist, K, Noinaj, N, Chazin, W, and Cornelissen, C. (2020). Molecular Insight Into TdfH-Mediated Zinc Piracy From Human Calprotectin by Neisseria Gonorrhoeae. mBio. 11(3). e00949-20.
Yadav, R, Noinaj, N, Ostan, N, Moraes, T, Stoudenmore, J, Maurakis, S, & Cornelissen, CN. (2020). Structural Basis for Evasion of Nutritional Immunity by the Pathogenic Neisseriae. Front Microbiol, 10(2981).
Celia, H, Noinaj, N, and Buchanon, SK. (2020). Structure and Stoichiometry of the Ton Molecular Motor. Int Jmol Sci, 21(2), E375.
Chen, D, Linjie, L, Diaz, K, Iyamu, Iredia, D. Yadav, R. Noinaj N, Huang, R. (2019). Novel Propargyl-Linked Bisubstrate Analogues as Tight-Binding Inhibitors for Nicotinamide N-Methyltransferase. J Med Chem, 62(23), 10783-10797.
Imai, Y., Meyer, K. J., Iinishi, A., Favre-Godal, Q., Green, R., Manuse, S., … Lewis, K. (2019). A new antibiotic selectively kills Gram-negative pathogens. Nature, 576, 459–464.
Wu, R. Stephenson, R. Gichaba, A. & Noinaj, N. (2019). The big BAM theory: An open and closed case? Biochimica et Biophysica Acta (BBA) - Biomembranes, 183062.
Chen, D, Dong, G, Noinaj, N, Huang, R. (2019) Discovery of Bisubstrate Inhibitors for Protein N-Terminal Methyltransferase 1. J Med Chem, 62(7):3773-3779.
Ha L, Colquhoun J, Noinaj N, Das C, Dunman P, and Flaherty D. (2018) Crystal structure of the ribonuclease P protein subunit from Staphylococcus aureus. Acta Cryst F 74(Pt 10):632-637.
Lundquist K, Bakelar J, Noinaj N, Gumbart JC. (2018) C-terminal kink formation is required for lateral gating in BamA. PNAS, 115(34):E7942-E7949 .
Sikora AE, Wierzbicki IH, Zielke RA, Ryner RF, Korotkov KV, Buchanan SK, and Noinaj N. (2018) Structural and functional insights into the role of BamD and BamE within the b-barrel assembly machinery in Neisseria gonorrhoeae. JBC, 293(4):1106-1119.